Jackie's friendship and professional association with Andy Warhol began in the mid-1960's. He appeared in Director Paul Morrissey's "Women in Revolt" with Candy Darling and Holly Woodlawn and "Flesh" with Joe Dallesandro and Candy Darling, presented by Andy Warhol. For these unique films director Morrissey gave the actors information about their character, the scene and suggested lines. The camera (frequently manned by Warhol) rolled and everyone improvised much of the content in a single take.

After his death in 1985, a friend found a note Jackie had written reading: "You are not truly a Warhol superstar unless you are dead."

In the late 60's, Jackie had "Andy" tatooed on his arm to demonstrate his devotion to Warhol.